CysLTR1 antibody (C-Term)

Catalog No. ABIN2788780

This Rabbit Polyclonal antibody specifically detects CysLTR1 in WB. It exhibits reactivity toward Human, Rabbit, Cow, Dog, Guinea Pig and Horse.

Quick Overview for CysLTR1 antibody (C-Term) (ABIN2788780)

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Reactivity: Human, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CysLTR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CysLTR1 Antibody

Binding Specificity: C-Term

Sequence: IIPFVIIIVC YTMIILTLLK KSMKKNLSSH KKAIGMIMVV TAAFLVSFMP

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against CYSLTR1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 337 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CysLTR1

Target: CysLTR1 (CYSLTR1) (Cysteinyl Leukotriene Receptor 1 (CYSLTR1))

Alternative Name: CYSLTR1

Background: The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
Alias Symbols: CYSLT1, CYSLT1R, CYSLTR, HG55, HMTMF81, MGC46139
Protein Interaction Partner: CYSLTR2,
Protein Size: 337

Molecular Weight: 37 kDa

Gene ID: 10800

NCBI Accession: NM_006639, NP_006630

UniProt: Q9Y271