PDLIM7 antibody (N-Term)

Catalog No. ABIN2788823

This Rabbit Polyclonal antibody specifically detects PDLIM7 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for PDLIM7 antibody (N-Term) (ABIN2788823)

Target: PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDLIM7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDLIM7 Antibody

Binding Specificity: N-Term

Sequence: RLMENTEDWR PRPGTGQSRS FRILAHLTGT EFMQDPDEEH LKKSSQVPRT

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PDLIM7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of HUMAN PDLIM7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDLIM7

Target: PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))

Alternative Name: PDLIM7

Background: The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.
Protein Interaction Partner: WWP2, IQGAP1, TSG101, PHF1, DGCR6, BAG3, RET, CBLC, COPS5, PARP1, YAP1, HNRNPD, PRKD2, ZMYND11, TRADD, UBC, SH3BP2, MYC, Hoxa1, NDUFA7, PCBP1, UBQLN4, TRAF3, TRAF2, TAB2, TRAF6, NR2C2, SMURF1, TP53, MDM2, Cdk1, PSMF1, SH2B2, C20orf195, AP5B1, ENKD1, TPM2,
Protein Size: 287

Molecular Weight: 31 kDa

Gene ID: 9260