RPL7 antibody (N-Term)

Catalog No. ABIN2788853

The Rabbit Polyclonal anti-RPL7 antibody has been validated for WB. It is suitable to detect RPL7 in samples from Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig and Rabbit.

Quick Overview for RPL7 antibody (N-Term) (ABIN2788853)

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPL7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPL7 Antibody

Binding Specificity: N-Term

Sequence: KKKRRNFAEL KIKRLRKKFA QKMLRKARRK LIYEKAKHYH KEYRQMYRTE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RPL7. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 248 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RPL7

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Alternative Name: RPL7

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: MGC117326, humL7-1, L7
Protein Interaction Partner: UBC, SUMO2, TUBGCP4, CEP250, TUBG1, TP53, STAU1, MDM2, LGR4, RPA3, RPA2, RPA1, RNF2, EED, PARK2, TARDBP, YWHAQ, PAN2, PHB, HSP90AB1, HSP90AA1, NOS2, IPO5, IL7R, FN1, ESR1, VCAM1, UBL4A, RAN, TRAF3IP1, EIF4A3, PPP1CC, MAGOH, HSP90AA5P, RPLP0P6, RPL10L, NIF
Protein Size: 248

Molecular Weight: 29 kDa

Gene ID: 6129

NCBI Accession: NM_000971, NP_000962

UniProt: P18124