Cullin 4A antibody (Middle Region)

Catalog No. ABIN2788865

This Rabbit Polyclonal antibody specifically detects Cullin 4A in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Horse, Rabbit, Dog, Cow and Guinea Pig.

Quick Overview for Cullin 4A antibody (Middle Region) (ABIN2788865)

Target: Cullin 4A (CUL4A)

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 4A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Cullin 4A Antibody

Binding Specificity: Middle Region

Sequence: SLACGKARVL IKSPKGKEVE DGDKFIFNGE FKHKLFRIKI NQIQMKETVE

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CUL4A. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 759 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cullin 4A

Target: Cullin 4A (CUL4A)

Alternative Name: CUL4A

Background: CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins.
Alias Symbols: -
Protein Interaction Partner: ERCC8, DCAF5, CHEK1, DDB2, DCAF15, DCAF11, DCAF17, DDA1, RFWD2, DCAF6, AMBRA1, DET1, PHIP, DCAF16, DTL, DCAF8, BPLF1, DCAF4, WDTC1, vpr, DAB2IP, UBC, NEDD8, DCUN1D2, DCUN1D1, HIST2H2BE, HIST4H4, HIST3H3, HIST1H1C, HIST2H2AC, ASB4, rev, PRMT5, CAST, DLC1,
Protein Size: 759

Molecular Weight: 88 kDa

Gene ID: 8451

NCBI Accession: NM_001008895, NP_001008895

UniProt: Q13619