Dematin antibody (Middle Region)

Catalog No. ABIN2788873

The Rabbit Polyclonal anti-Dematin antibody has been validated for WB. It is suitable to detect Dematin in samples from Human, Mouse, Cow, Rat, Dog, Guinea Pig and Horse.

Quick Overview for Dematin antibody (Middle Region) (ABIN2788873)

Target: Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))

Reactivity: Human, Mouse, Cow, Rat, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dematin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Dematin Antibody

Binding Specificity: Middle Region

Sequence: KKPPIYKQRE SVGGSPQTKH LIEDLIIESS KFPAAQPPDP NQPAKIETDY

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EPB49. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 405 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Dematin

Target: Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))

Alternative Name: EPB49

Background: Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation.
Alias Symbols: DMT, FLJ78462, FLJ98848, EPB49
Protein Interaction Partner: GOLGA2, YWHAB, APP, NEDD4L, SNCA, PTOV1, DYNC1LI2, PRKACA, SNRPD2, PROCR, SPTB, EPB42, ACTB, ACTC1, DISC1,
Protein Size: 405

Molecular Weight: 45 kDa

Gene ID: 2039

NCBI Accession: NM_001978, NP_001969

UniProt: Q08495

Pathways: Regulation of Actin Filament Polymerization