VAC14 antibody (C-Term)

Catalog No. ABIN2788881

This Rabbit Polyclonal antibody specifically detects VAC14 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Guinea Pig, Rabbit, Horse and Pig.

Quick Overview for VAC14 antibody (C-Term) (ABIN2788881)

Target: VAC14 (Vac14 Homolog (VAC14))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Rabbit, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAC14 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VAC14 Antibody

Binding Specificity: C-Term

Sequence: QLLSHRLQCV PNPELLQTED SLKAAPKSQK ADSPSIDYAE LLQHFEKVQN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 77%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 79%, Rabbit: 79%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against VAC14. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 781 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VAC14

Target: VAC14 (Vac14 Homolog (VAC14))

Alternative Name: VAC14

Background: The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE and the PtdIns(3,5)P2 phosphatase FIG4. VAC14 functions as an activator of PIKFYVE.
Alias Symbols: ArPIKfyve, FLJ10305, FLJ36622, FLJ46582, MGC149815, MGC149816, TAX1BP2, TRX
Protein Interaction Partner: LINC00518, PIKFYVE, TCEANC, MGAT5B, C4orf33, PRR20A, PHYKPL, ACSS1, RHOXF2, PRADC1, ZNF34, LPAL2, ASB13, MTMR9, FNDC3B, NGB, SPRYD7, PELI1, PCMTD2, WDYHV1, PRR13, CD209, C11orf54, SMUG1, DDAH2, RBFOX2, SNF8, PDE4DIP, SIGLEC5, BHLHE40, TP53BP1, PPP2CA, PHF
Protein Size: 781

Molecular Weight: 86 kDa

Gene ID: 55697

NCBI Accession: NM_018052, NP_060522

UniProt: Q08AM6

Pathways: Inositol Metabolic Process