FPGT antibody (C-Term)

Catalog No. ABIN2789255

The Rabbit Polyclonal anti-FPGT antibody has been validated for WB. It is suitable to detect FPGT in samples from Human, Mouse, Guinea Pig, Cow, Dog, Pig, Rat and Saccharomyces cerevisiae.

Quick Overview for FPGT antibody (C-Term) (ABIN2789255)

Target: FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

Reactivity: Human, Mouse, Guinea Pig, Cow, Dog, Pig, Rat, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FPGT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FPGT Antibody

Binding Specificity: C-Term

Sequence: SLKMNRCLKY ATMAFGVQDN LKKSVKTLSD IKLLQFFGVC FLSCLDVWNL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 77%, Human: 100%, Mouse: 85%, Pig: 93%, Rat: 92%, Yeast: 91%

Characteristics: This is a rabbit polyclonal antibody against FPGT. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 340 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FPGT

Target: FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))

Alternative Name: FPGT

Background: L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene.
Alias Symbols: GFPP
Protein Interaction Partner: NLN,
Protein Size: 340

Molecular Weight: 37 kDa

Gene ID: 8790

NCBI Accession: NM_001199328, NP_001186257

UniProt: E9PNQ2