SRI antibody (Middle Region)

Catalog No. ABIN2789323

This Rabbit Polyclonal antibody specifically detects SRI in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Dog, Cow, Rabbit, Sheep, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for SRI antibody (Middle Region) (ABIN2789323)

Target: SRI (Sorcin (SRI))

Reactivity: Human, Mouse, Rat, Horse, Dog, Cow, Rabbit, Sheep, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRI antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SRI Antibody

Binding Specificity: Middle Region

Sequence: KELWAVLNGW RQHFISFDTD RSGTVDPQEL QKALTTMGFR LSPQAVNSIA

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%, Sheep: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SRI. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 198 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRI

Target: SRI (Sorcin (SRI))

Alternative Name: SRI

Background: SRI is a calcium-binding protein that modulates excitation-contraction coupling in the heart. It contributes to calcium homeostasis in the heart sarcoplasmic reticulum. It modulates the activity of RYR2 calcium channels.
Alias Symbols: FLJ26259, SCN, CP22
Protein Interaction Partner: PRR13, CALCOCO2, TCF12, PDE4C, GCA, STAT3, SRI, HAUS2, UBC, SRPK2, VCAM1, SMAD2, ITGA4, FN1, SNCA, SHBG, NRAS, RUVBL1, ANXA11, PSEN2, ANXA7, RYR2, CACNA1S, CACNA1C, ALG2,
Protein Size: 198

Molecular Weight: 22 kDa

Gene ID: 6717

NCBI Accession: NM_003130, NP_003121

UniProt: P30626

Pathways: Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity