NOS2 antibody (N-Term)

Catalog No. ABIN2789330

This anti-NOS2 antibody is a Rabbit Polyclonal antibody detecting NOS2 in WB and IHC. Suitable for Human.

Quick Overview for NOS2 antibody (N-Term) (ABIN2789330)

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NOS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NOS2 Antibody

Binding Specificity: N-Term

Sequence: PCATSSPVTQ DDLQYHNLSK QQNESPQPLV ETGKKSPESL VKLDATPLSS

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against NOS2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 997 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NOS2

Target: NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

Alternative Name: NOS2

Background: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.
Alias Symbols: HEP-NOS, INOS, NOS, NOS2A
Protein Interaction Partner: CUL5, SPSB2, NOS2, CALM1, HSP90AA1, CCT7, AGR2, CDIPT, DNAJA2, PSMD14, HUWE1, PSMD6, BAG2, RPL23, AIFM1, DNAJA3, HERC1, SLC7A5, YWHAZ, YWHAG, YWHAE, XRCC5, VCP, UBC, DNAJC7, CCT3, TNFAIP2, TCP1, TCEB2, SSR4, SSBP1, TRIM21, SNRPD3, SNRPB, SMN1, SLC3A2, SKP
Protein Size: 997

Molecular Weight: 110 kDa

Gene ID: 4843

NCBI Accession: NM_000625

UniProt: P35228

Pathways: Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process