TES antibody (Middle Region)

Catalog No. ABIN2789357

Product Details anti-TES Antibody

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Binding Specificity: Middle Region

Reactivity: Human, Cow, Dog, Guinea Pig, Sheep, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TES antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PKQMNIPGGD RSTPAAVGAM EDKSAEHKRT QYSCYCCKLS MKEGDPAIYA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 91%, Horse: 79%, Human: 100%, Pig: 93%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against TES. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 421 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TES

Target: TES (Testis Derived Transcript (3 LIM Domains) (TES))

Alternative Name: TES (TES Products)

Background: Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.
Alias Symbols: DKFZp586B2022, MGC1146, TESS, TESS-2
Protein Interaction Partner: SUMO2, VPS25, RPRD1B, OSGEP, NAGK, HNRNPUL1, EPRS, EVL, SOCS3, SPTAN1, THADA, AHCYL1, SSSCA1, ZPR1, IGBP1, ELAVL1, UBC, ARAP1, Cep350, ENAH, SPOCK2, ACTL7A, TES, ZYX, VASP, GRIPAP1, TLN1, ACTN1, RAB8B, ACTA1, GRIP1,
Protein Size: 421

Molecular Weight: 47 kDa

Gene ID: 26136

NCBI Accession: NM_015641, NP_056456

UniProt: Q9UGI8