NPL antibody (N-Term)

Catalog No. ABIN2789414

Product Details anti-NPL Antibody

Target: NPL (N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase) (NPL))

Binding Specificity: N-Term

Reactivity: Human, Rat, Dog, Horse, Pig, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPL antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SERRQVAEEW VTKGKDKLDQ VIIHVGALSL KESQELAQHA AEIGADGIAV

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against NPL. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 230 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPL

Target: NPL (N-Acetylneuraminate Pyruvate Lyase (Dihydrodipicolinate Synthase) (NPL))

Alternative Name: NPL (NPL Products)

Background: This gene encodes a member of the N-acetylneuraminate lyase sub-family of (beta/alpha)(8)-barrel enzymes. N-acetylneuraminate lyases regulate cellular concentrations of N-acetyl-neuraminic acid (sialic acid) by mediating the reversible conversion of sialic acid into N-acetylmannosamine and pyruvate. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: C1orf13, DHDPS1, MGC149582, MGC61869, NPL1, c112, NAL, C112
Protein Interaction Partner: NPL, WDYHV1, APP,
Protein Size: 230

Molecular Weight: 25 kDa

Gene ID: 80896

NCBI Accession: NM_001200052, NP_001186981

UniProt: Q9BXD5