PMP22 antibody (N-Term)

Catalog No. ABIN2789416

This anti-PMP22 antibody is a Rabbit Polyclonal antibody detecting PMP22 in WB. Suitable for Human, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse and Sheep.

Quick Overview for PMP22 antibody (N-Term) (ABIN2789416)

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Reactivity: Human, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PMP22 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PMP22 Antibody

Binding Specificity: N-Term

Sequence: QWIVGNGHAT DLWQNCSTSS SGNVHHCFSS SPNEWLQSVQ ATMILSIIFS

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Rabbit: 100%, Rat: 93%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against PMP22. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of PMP22

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 160 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PMP22

Target: PMP22 (Peripheral Myelin Protein 22 (PMP22))

Alternative Name: PMP22

Background: This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing of this gene results in three transcript variants that encode the same protein.
Alias Symbols: CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, MGC20769, Sp110
Protein Interaction Partner: SMIM3, KLRC1, PEX19, DDX52, ELAVL1, MPZ, CANX,
Protein Size: 160

Molecular Weight: 18 kDa

Gene ID: 5376

NCBI Accession: NM_153321, NP_696996

UniProt: Q01453