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PD-L1 antibody (C-Term)

This anti-PD-L1 antibody is a Rabbit Polyclonal antibody detecting PD-L1 in WB. Suitable for Human, Pig and Cow.
Catalog No. ABIN2789466

Quick Overview for PD-L1 antibody (C-Term) (ABIN2789466)

Target

See all PD-L1 Antibodies
PD-L1 (CD274 (PD-L1))

Reactivity

  • 273
  • 142
  • 72
  • 6
  • 5
  • 5
  • 4
  • 1
  • 1
Human, Pig, Cow

Host

  • 154
  • 144
  • 20
  • 5
  • 4
  • 4
  • 2
  • 1
Rabbit

Clonality

  • 204
  • 121
  • 7
Polyclonal

Conjugate

  • 157
  • 26
  • 14
  • 12
  • 9
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This PD-L1 antibody is un-conjugated

Application

  • 193
  • 146
  • 95
  • 74
  • 45
  • 45
  • 44
  • 40
  • 28
  • 15
  • 11
  • 10
  • 7
  • 7
  • 5
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 72
    • 29
    • 16
    • 15
    • 14
    • 11
    • 11
    • 9
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequence

    NVTSTLRINT TTNEIFYCTF RRLDPEENHT AELVIPELPL AHPPNERTHL

    Predicted Reactivity

    Cow: 79%, Human: 100%, Pig: 100%

    Characteristics

    This is a rabbit polyclonal antibody against CD274. It was validated on Western Blot.

    Purification

    Affinity Purified
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 290 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    PD-L1 (CD274 (PD-L1))

    Alternative Name

    CD274

    Background

    CD274 is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
    Alias Symbols: B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1, PDCD1LG1, PDL1
    Protein Interaction Partner: PDCD1, CD80, PTPN11,
    Protein Size: 290

    Molecular Weight

    32 kDa

    Gene ID

    29126

    NCBI Accession

    NM_014143, NP_054862

    UniProt

    Q9NZQ7

    Pathways

    Cancer Immune Checkpoints
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