RPL22 antibody (C-Term)

Catalog No. ABIN2789542

This Rabbit Polyclonal antibody specifically detects RPL22 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for RPL22 antibody (C-Term) (ABIN2789542)

Target: RPL22 (Ribosomal Protein L22 (RPL22))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPL22 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RPL22 Antibody

Binding Specificity: C-Term

Sequence: TSEVPFSKRY LKYLTKKYLK KNNLRDWLRV VANSKESYEL RYFQINQDEE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RPL22. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 128 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RPL22

Target: RPL22 (Ribosomal Protein L22 (RPL22))

Alternative Name: RPL22

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3,21 translocations, however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2.
Alias Symbols: EAP, HBP15, HBP15/L22, L22
Protein Interaction Partner: HUWE1, CEP76, CEP57, VCP, UBC, TUBG1, AURKA, RNF2, EED, HEXB, ARFGAP1, GTF3C4, PARK2, TARDBP, SRPK2, IGSF8, ICAM1, MAPK14, CDK2, CD81, PAN2, UBL4A, VCAM1, ITGA4, IL7R, FN1, SMURF1, ESR1, HNRNPM, RPSA, ILF3, HSP90AA4P, DHX15, RPLP0P6, RPL10L, RPS27L, STRAP
Protein Size: 128

Molecular Weight: 14 kDa

Gene ID: 6146

NCBI Accession: NM_000983, NP_000974

UniProt: P35268