TNFAIP6 antibody (C-Term)
Quick Overview for TNFAIP6 antibody (C-Term) (ABIN2789586)
Target
See all TNFAIP6 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- DIISTGNVMT LKFLSDASVT AGGFQIKYVA MDPVSKSSQG KNTSTTSTGN
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Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 93%
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Characteristics
- This is a rabbit polyclonal antibody against TNFAIP6. It was validated on Western Blot.
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Purification
- Affinity Purified
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 277 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TNFAIP6 (Tumor Necrosis Factor-Inducible Protein 6 (TNFAIP6))
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Alternative Name
- TNFAIP6
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Background
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The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
Alias Symbols: TSG-6, TSG6
Protein Interaction Partner: UBC, THBS1, ACAN,
Protein Size: 277 -
Molecular Weight
- 30 kDa
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Gene ID
- 7130
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NCBI Accession
- NM_007115, NP_009046
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UniProt
- P98066
Target
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