FUT3 antibody (C-Term)

Catalog No. ABIN2789676

This anti-FUT3 antibody is a Rabbit Polyclonal antibody detecting FUT3 in WB. Suitable for Human, Cow and Dog.

Quick Overview for FUT3 antibody (C-Term) (ABIN2789676)

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Reactivity: Human, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUT3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FUT3 Antibody

Binding Specificity: C-Term

Sequence: DKDHARYLSY FRWRETLRPR SFSWALDFCK ACWKLQQESR YQTVRSIAAW

Predicted Reactivity: Cow: 86%, Dog: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against FUT3. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 361 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FUT3

Target: FUT3 (Fucosyltransferase 3 (Galactoside 3(4)-L-Fucosyltransferase, Lewis Blood Group) (FUT3))

Alternative Name: FUT3

Background: The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
Alias Symbols: CD174, FT3B, FucT-III, LE, Les, MGC131739
Protein Size: 361

Molecular Weight: 42 kDa

Gene ID: 2525

NCBI Accession: NM_000149, NP_000140

UniProt: P21217