BRMS1 antibody (C-Term)

Catalog No. ABIN2789686

This Rabbit Polyclonal antibody specifically detects BRMS1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog and Sheep.

Quick Overview for BRMS1 antibody (C-Term) (ABIN2789686)

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Dog, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRMS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BRMS1 Antibody

Binding Specificity: C-Term

Sequence: HARGSSRSWD SLPPSKRKKA PLVSGPYIVY MLQEIDILED WTAIKKARAA

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against BRMS1. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 290 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BRMS1

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Alternative Name: BRMS1

Background: This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
Alias Symbols: DKFZp564A063
Protein Interaction Partner: CEP70, NMI, HDAC2, HDAC1, SIN3A, APP, BRMS1L, ING1, HDAC6, HDAC4, TAF1, SMARCE1, SMTN, ARID4A, KPNA5, HSP90AA1, HSPA4, HDAC5, SUDS3, DNAJB6, UBC, SAP25, RELA, NFKB1, HDAC3, LRIF1, RBP1, PFDN5, DNAJB1, SAP30, RBBP4, RBBP7, GOLGB1, EEF1A1,
Protein Size: 290

Molecular Weight: 34 kDa

Gene ID: 25855

NCBI Accession: NM_001024957, NP_001020128

UniProt: G5E9I4