NTSR2 antibody (C-Term)

Catalog No. ABIN2789746

This Rabbit Polyclonal antibody specifically detects NTSR2 in WB. It exhibits reactivity toward Human, Horse and Saccharomyces cerevisiae.

Quick Overview for NTSR2 antibody (C-Term) (ABIN2789746)

Target: NTSR2 (Neurotensin Receptor 2 (NTSR2))

Reactivity: Human, Horse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NTSR2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NTSR2 Antibody

Binding Specificity: C-Term

Sequence: AFLNGVTVSH LLALCSQVPS TSTPGSSTPS RLELLSEEGL LSFIVWKKTF

Predicted Reactivity: Horse: 77%, Human: 100%, Yeast: 85%

Characteristics: This is a rabbit polyclonal antibody against NTSR2. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 410 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NTSR2

Target: NTSR2 (Neurotensin Receptor 2 (NTSR2))

Alternative Name: NTSR2

Background: The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist.
Alias Symbols: NTR2
Protein Interaction Partner: NTS,
Protein Size: 410

Molecular Weight: 45 kDa

Gene ID: 23620

NCBI Accession: NM_012344, NP_036476

UniProt: O95665