MPP1 antibody (N-Term)
Quick Overview for MPP1 antibody (N-Term) (ABIN2789786)
Target
See all MPP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- APGSPAQVKG QEVRKVRLIQ FEKVTEEPMG ITLKLNEKQS CTVARILHGG
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Predicted Reactivity
- Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 77%, Rabbit: 86%, Rat: 85%
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Characteristics
- This is a rabbit polyclonal antibody against MPP1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 436 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MPP1 (Membrane Protein, Palmitoylated 1, 55kDa (MPP1))
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Alternative Name
- MPP1
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Background
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This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells.
Alias Symbols: AAG12, DXS552E, EMP55, MRG1, PEMP
Protein Interaction Partner: KLHL12, DNPEP, UBC, HNRNPD, ERBB2IP, FN1, NR1H2, TK1, STK3, SMN1, RPS6KA1, GSK3B, GADD45A, ZAK, RPS6KA6, OPTN, AMOTL2, SGSM2, STUB1, GYPC, ATP5C1,
Protein Size: 436 -
Molecular Weight
- 47 kDa
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Gene ID
- 4354
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NCBI Accession
- NM_001166462, NP_001159934
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UniProt
- B4DZV5
Target
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