GPC4 antibody (C-Term)

Catalog No. ABIN2789855

This Rabbit Polyclonal antibody specifically detects GPC4 in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Cow and Guinea Pigand has been mentioned in 1 publication.

Quick Overview for GPC4 antibody (C-Term) (ABIN2789855)

Target: GPC4 (Glypican 4 (GPC4))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GPC4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GPC4 Antibody

Binding Specificity: C-Term

Sequence: EYQQCPSEFD YNATDHAGKS ANEKADSAGV RPGAQAYLLT VFCILFLVMQ

Predicted Reactivity: Cow: 79%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against GPC4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human GPC4

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GPC4 antibody (ABIN2789855)

Walshe, Harkin: "Serial explant culture provides novel insights into the potential location and phenotype of corneal endothelial progenitor cells." in: Experimental eye research, Vol. 127, pp. 9-13, (2014) (PubMed).

Target Details for GPC4

Target: GPC4 (Glypican 4 (GPC4))

Alternative Name: GPC4

Background: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.
Alias Symbols: K-glypican
Protein Size: 486

Molecular Weight: 53 kDa

Gene ID: 2239

NCBI Accession: NM_001448, NP_001439

UniProt: B4E2C0

Pathways: Glycosaminoglycan Metabolic Process