KRT4 antibody (N-Term)

Catalog No. ABIN2790009

This anti-KRT4 antibody is a Rabbit Polyclonal antibody detecting KRT4 in WB. Suitable for Human, Rat, Mouse, Cow, Dog, Pig, Rabbit, Horse and Sheep.

Quick Overview for KRT4 antibody (N-Term) (ABIN2790009)

Target: KRT4 (Keratin 4 (KRT4))

Reactivity: Human, Rat, Mouse, Cow, Dog, Pig, Rabbit, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KRT4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KRT4 Antibody

Binding Specificity: N-Term

Sequence: SGKGGPGFPV CPAGGIQEVT INQSLLTPLH VEIDPEIQKV RTEEREQIKL

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 100%, Rat: 100%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against KRT4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 520 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KRT4

Target: KRT4 (Keratin 4 (KRT4))

Alternative Name: KRT4

Background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Alias Symbols: CK4, CYK4, FLJ31692, K4, CK-4
Protein Interaction Partner: KRT40, KRT38, KRT33B, KRT15, KRT13, WWOX, UBASH3B, SHC1, PIK3R2, GRB2, EPS15, CRK, CUL3, UBC, ATG4B, USP25, USPL1, USP1, UCHL1,
Protein Size: 520

Molecular Weight: 56 kDa

Gene ID: 3851

NCBI Accession: NM_002272, NP_002263

UniProt: F8VS64