CDNF antibody (N-Term)
Quick Overview for CDNF antibody (N-Term) (ABIN2790078)
Target
See all CDNF AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- IDRGVNFSLD TIEKELISFC LDTKGKENRL CYYLGATKDA ATKILSEVTR
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Predicted Reactivity
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%
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Characteristics
- This is a rabbit polyclonal antibody against CDNF. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CDNF
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 187 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
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Alternative Name
- CDNF
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Background
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CDNF is a trophic factor for dopamine neurons. CDNF prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, CDNF restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra.
Alias Symbols: ARMETL1
Protein Size: 187 -
Molecular Weight
- 21 kDa
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Gene ID
- 441549
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NCBI Accession
- NM_001029954, NP_001025125
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UniProt
- Q49AH0
Target
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