IL22RA2 antibody (C-Term)

Catalog No. ABIN2790188

The Rabbit Polyclonal anti-IL22RA2 antibody has been validated for WB. It is suitable to detect IL22RA2 in samples from Human and Dog.

Quick Overview for IL22RA2 antibody (C-Term) (ABIN2790188)

Target: IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL22RA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL22RA2 Antibody

Binding Specificity: C-Term

Sequence: NITQVNGSLL VILHAPNLPY RYQKEKNVSI EDYYELLYRV FIINNSLEKE

Predicted Reactivity: Dog: 86%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against IL22RA2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL22RA2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 263 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL22RA2

Target: IL22RA2 (Interleukin 22 Receptor, alpha 2 (IL22RA2))

Alternative Name: IL22RA2

Background: The protein encoded by this gene is a soluble class II cytokine receptor. This protein has been shown to specifically bind to interleukin 22 (IL22), block the interaction of IL22 with its cell surface receptor, and thus inhibit IL22 activity. This protein functions as an IL22 antagonist, and may be important in the regulation of inflammatory response. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: CRF2-10, CRF2-S1, CRF2X, IL-22BP, MGC150509, MGC150510
Protein Interaction Partner: IL22,
Protein Size: 263

Molecular Weight: 26 kDa

Gene ID: 116379

NCBI Accession: NM_052962, NP_443194

UniProt: Q969J5