PPP1CB antibody (C-Term)

Catalog No. ABIN2790274

Product Details anti-PPP1CB Antibody

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1CB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LFSAPNYCGE FDNAGGMMSV DETLMCSFQI LKPSEKKAKY QYGGLNSGRP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PPP1CB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PPP1CB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 327 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP1CB

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Alternative Name: PPP1CB (PPP1CB Products)

Background: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Mouse studies suggest that PP1 functions as a suppressor of learning and memory. Two alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MGC3672, PP-1B, PP1beta, PPP1CD
Protein Interaction Partner: PPP1R3C, PPP1R2P3, PPP1R16A, CSRNP2, SH2D4A, UBC, TP53BP2, SUMO2, SUMO3, NUAK1, EED, DENR, MVK, EEF1A1, DHX15, PAN2, RHO, ZFYVE9, MDM4, KAT8, WDR5, PAPOLA, OGT, AURKA, PPP1CA, HCFC1, CUL3, PTK2, MAX, LBR, HSPA4, CDKN2A, CDC34, CCND3, CCNB1, BCL2, CCND1, S
Protein Size: 327

Molecular Weight: 37 kDa

Gene ID: 5500

NCBI Accession: NM_002709, NP_002700

UniProt: P62140

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism