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PPP1CB antibody (Catalytic Subunit)

PPP1CB Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7169308
  • Target See all PPP1CB Antibodies
    PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))
    Binding Specificity
    • 15
    • 13
    • 10
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 175-221, Catalytic Subunit
    Reactivity
    • 66
    • 37
    • 23
    • 10
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 61
    • 8
    • 4
    • 1
    Rabbit
    Clonality
    • 68
    • 6
    Polyclonal
    Conjugate
    • 42
    • 7
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPP1CB antibody is un-conjugated
    Application
    • 52
    • 39
    • 10
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human Serine/threonine-protein phosphatase PP1-beta catalytic subunit protein (175-221AA)
    Isotype
    IgG
    Top Product
    Discover our top product PPP1CB Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))
    Alternative Name
    PPP1CB (PPP1CB Products)
    Synonyms
    PP-1B antibody, PP1B antibody, PP1beta antibody, PPP1CD antibody, 1200010B19 antibody, ik:tdsubc_2f2 antibody, si:zc214p16.4 antibody, wu:fa09h01 antibody, wu:fa11e06 antibody, xx:tdsubc_2f2 antibody, PP2CB antibody, Ppp1cb antibody, protein phosphatase 1 catalytic subunit beta antibody, protein phosphatase 1, catalytic subunit, beta isoform antibody, protein phosphatase 1, catalytic subunit, beta isozyme L homeolog antibody, protein phosphatase 1, catalytic subunit, beta isozyme antibody, serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody, protein phosphatase 1B, magnesium dependent, beta isoform antibody, PPP1CB antibody, Ppp1cb antibody, ppp1cb.L antibody, ppp1cb antibody, LOC100224238 antibody, Ppm1b antibody
    Background

    Background: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the \\\'Ser-418\\\' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).

    Aliases: MGC3672 antibody, PP 1B antibody, PP-1B antibody, PP1B antibody, PP1B_HUMAN antibody, PP1beta antibody, PPP1CB antibody, PPP1CD antibody, Protein phosphatase 1 beta antibody, Protein phosphatase 1 catalytic subunit beta isoform antibody, Protein phosphatase 1 delta antibody, Protein phosphatase 1, catalytic subunit, beta isozyme antibody, Protein phosphatase 1, catalytic subunit, delta isoform antibody, Serine threonine protein phosphatase PP1 beta catalytic subunit antibody, Serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody

    UniProt
    P62140
    Pathways
    M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
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