PPP1CB antibody (Catalytic Subunit)

Catalog No. ABIN7177855

The Rabbit Polyclonal anti-PPP1CB antibody (ABIN7177855) specifically detects PPP1CB in WB and ELISA. The antibody is reactive with Mouse samples.

Quick Overview for PPP1CB antibody (Catalytic Subunit) (ABIN7177855)

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1CB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PPP1CB Antibody

Binding Specificity: AA 2-327, Catalytic Subunit

Purpose: Ppp1cb Antibody

Cross-Reactivity: Rat

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Mouse Serine/threonine-protein phosphatase PP1-beta catalytic subunit protein (2-327AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PPP1CB

Target: PPP1CB (Protein Phosphatase 1, Catalytic Subunit, beta Isoform (PPP1CB))

Alternative Name: Ppp1cb

Background:

Background: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E.

Aliases: Ppp1cb antibody, Serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody, PP-1B antibody, EC 3.1.3.16 antibody, EC 3.1.3.53 antibody

UniProt: P62141

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism