STAG2 antibody (C-Term)

Catalog No. ABIN2790312

This anti-STAG2 antibody is a Rabbit Polyclonal antibody detecting STAG2 in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Horse and Zebrafish (Danio rerio).

Quick Overview for STAG2 antibody (C-Term) (ABIN2790312)

Target: STAG2 (Stromal Antigen 2 (STAG2))

Reactivity: Human, Mouse, Rat, Dog, Cow, Pig, Rabbit, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAG2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STAG2 Antibody

Binding Specificity: C-Term

Sequence: LLAGGDDDTM SVISGISSRG STVRSKKSKP STGKRKVVEG MQLSLTEESS

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against STAG2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human STAG2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1231 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STAG2

Target: STAG2 (Stromal Antigen 2 (STAG2))

Alternative Name: STAG2

Background: STAG2 is a component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
Alias Symbols: DKFZp686P168, DKFZp781H1753, FLJ25871, SA-2, SA2, bA517O1.1, SCC3B
Protein Interaction Partner: UBC, CDCA5, HDAC8, VCP, SRRM2, RBM14, SFPQ, RAD21, PLK1, NHP2L1, NSMCE2, UBD, SIRT7, SUMO2, SMC3, SMC1A, PDS5A, PDS5B, Stag2, WAPAL, WFDC5, SSU72, SRRM1, STAG1,
Protein Size: 1231

Molecular Weight: 141 kDa

Gene ID: 10735

NCBI Accession: NM_006603, NP_006594

UniProt: Q8N3U4

Pathways: Stem Cell Maintenance