Keratin 85 antibody (N-Term)
Quick Overview for Keratin 85 antibody (N-Term) (ABIN2790418)
Target
See all Keratin 85 (KRT85) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- CGPSPPCITT VSVNESLLTP LNLEIDPNAQ CVKQEEKEQI KSLNSRFAAF
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Predicted Reactivity
- Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 86%, Sheep: 92%
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Characteristics
- This is a rabbit polyclonal antibody against KRT85. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human KRT85
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 507 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Keratin 85 (KRT85)
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Alternative Name
- KRT85
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Background
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The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.
Alias Symbols: HB5, Hb-5, KRTHB5, hHb5
Protein Interaction Partner: UBC, GRB2, EPS15, CUL3, CUL4B, ATG10, ATG3, MLST8, OTUD4, USPL1, USP15, USP8, ALOX12, LYAR, PLEKHB2, TWF2, YWHAG, DLG3, CDC25B, CDC20,
Protein Size: 507 -
Molecular Weight
- 56 kDa
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Gene ID
- 3891
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NCBI Accession
- NM_002283, NP_002274
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UniProt
- P78386
Target
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