CNOT6L antibody (Middle Region)
CNOT6L
Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
WB
Host: Rabbit
Polyclonal
unconjugated
1 image
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- Target See all CNOT6L Antibodies
- CNOT6L (CCR4-NOT Transcription Complex, Subunit 6-Like (CNOT6L))
- Binding Specificity
- Middle Region
- Reactivity
- Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Western Blotting (WB)
- Sequence
- AKIMSEQERK HVDGCAIFFK TEKFTLVQKH TVEFNQVAMA NSDGSEAMLN
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Characteristics
- This is a rabbit polyclonal antibody against CNOT6L. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human CNOT6L
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CNOT6L (CCR4-NOT Transcription Complex, Subunit 6-Like (CNOT6L))
- Alternative Name
- CNOT6L
- Background
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CNOT6L plays a role in the deadenylation of mRNAs in the cytoplasm. Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. It may be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA.
Protein Interaction Partner: TNKS1BP1, CNOT10, CNOT1, CHAF1A, RQCD1, CHAF1B, CNOT3, CNOT2, ZSCAN1, LZTR1, BTG2,
Protein Size: 475 - Molecular Weight
- 52 kDa
- Gene ID
- 246175
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