CNOT6L antibody (Middle Region)

Catalog No. ABIN2790464

The Rabbit Polyclonal anti-CNOT6L antibody (ABIN2790464) specifically detects CNOT6L in WB. The antibody is reactive with Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat and Zebrafish (Danio rerio) samples.

Quick Overview for CNOT6L antibody (Middle Region) (ABIN2790464)

Target: CNOT6L (CCR4-NOT Transcription Complex, Subunit 6-Like (CNOT6L))

Reactivity: Human, Cow, Dog, Guinea Pig, Horse, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT6L antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CNOT6L Antibody

Binding Specificity: Middle Region

Sequence: AKIMSEQERK HVDGCAIFFK TEKFTLVQKH TVEFNQVAMA NSDGSEAMLN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CNOT6L. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CNOT6L

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNOT6L

Target: CNOT6L (CCR4-NOT Transcription Complex, Subunit 6-Like (CNOT6L))

Alternative Name: CNOT6L

Background: CNOT6L plays a role in the deadenylation of mRNAs in the cytoplasm. Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. It may be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA.
Protein Interaction Partner: TNKS1BP1, CNOT10, CNOT1, CHAF1A, RQCD1, CHAF1B, CNOT3, CNOT2, ZSCAN1, LZTR1, BTG2,
Protein Size: 475

Molecular Weight: 52 kDa

Gene ID: 246175