COX6B1 antibody (N-Term)
Quick Overview for COX6B1 antibody (N-Term) (ABIN2790530)
Target
See all COX6B1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- TAPFDSRFPN QNQTRNCWQN YLDFHRCQKA MTAKGGDISV CEWYQRVYQS
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 93%
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Characteristics
- This is a rabbit polyclonal antibody against COX6B1. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human COX6B1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 86 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- COX6B1 (Cytochrome C Oxidase Subunit VIb Polypeptide 1 (Ubiquitous) (COX6B1))
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Alternative Name
- COX6B1
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Background
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Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.
Alias Symbols: COX6B, COXG, COXVIb1
Protein Interaction Partner: UBC, MDM2, env, Htt, ACOX1, NELFCD,
Protein Size: 86 -
Molecular Weight
- 10 kDa
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Gene ID
- 1340
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NCBI Accession
- NM_001863, NP_001854
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UniProt
- P14854
Target
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