MAPRE2 antibody (C-Term)
Quick Overview for MAPRE2 antibody (C-Term) (ABIN2790560)
Target
See all MAPRE2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- LLCQEHGQEN DDLVQRLMDI LYASEEHEGH TEEPEAEEQA HEQQPPQQEE
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Predicted Reactivity
- Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%, Yeast: 75%
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Characteristics
- This is a rabbit polyclonal antibody against MAPRE2. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MAPRE2
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 327 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAPRE2 (Microtubule-Associated Protein, RP/EB Family, Member 2 (MAPRE2))
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Alternative Name
- MAPRE2
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Background
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The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: EB1, EB2, RP1
Protein Interaction Partner: CRTAC1, TXN2, PAXIP1, MAPRE1, MAPRE2, TRAIP, HUWE1, TRAF1, LMO2, UBC, AURKB, AURKA, CDK4, CDK2, TRAF3IP1, LRRC1, DGCR8, APP, RNF185, MAPRE3, CLASP2, NIF3L1, CLIP1, APC,
Protein Size: 327 -
Molecular Weight
- 36 kDa
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Gene ID
- 10982
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NCBI Accession
- NM_014268, NP_055083
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UniProt
- Q15555
Target
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