NADSYN1 antibody (C-Term)

Catalog No. ABIN2790661

This Rabbit Polyclonal antibody specifically detects NADSYN1 in WB. It exhibits reactivity toward Human, Cow, Dog, Guinea Pig, Rat, Goat, Horse, Mouse and Saccharomyces cerevisiaeand has been mentioned in 1 publication.

Quick Overview for NADSYN1 antibody (C-Term) (ABIN2790661)

Target: NADSYN1 (NAD Synthetase 1 (NADSYN1))

Reactivity: Human, Cow, Dog, Guinea Pig, Rat, Goat, Horse, Mouse, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NADSYN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NADSYN1 Antibody

Binding Specificity: C-Term

Sequence: PAYHAENYSP EDNRFDLRPF LYNTSWPWQF RCIENQVLQL ERAEPQSLDG

Predicted Reactivity: Cow: 86%, Dog: 86%, Goat: 85%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%, Yeast: 93%

Characteristics: This is a rabbit polyclonal antibody against NADSYN1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NADSYN1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 706 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NADSYN1 antibody (ABIN2790661)

Yue, Chen, Xie, Hao, Guo, Sun, Jia, Zhang, Zhou, Zhong: "Activation of PPARα-catalase pathway reverses alcoholic liver injury via upregulating NAD synthesis and accelerating alcohol clearance." in: Free radical biology & medicine, Vol. 174, pp. 249-263, (2021) (PubMed).

Target Details for NADSYN1

Target: NADSYN1 (NAD Synthetase 1 (NADSYN1))

Alternative Name: NADSYN1

Background: Nicotinamide adenine dinucleotide (NAD) is a coenzyme in metabolic redox reactions, a precursor for several cell signaling molecules, and a substrate for protein posttranslational modifications. NAD synthetase (EC 6.3.5.1) catalyzes the final step in the biosynthesis of NAD from nicotinic acid adenine dinucleotide (NaAD).
Alias Symbols: FLJ10631, FLJ36703, FLJ40627
Protein Interaction Partner: MYO15B, STUB1, AIP, UPF1, UBC, UBD, NADSYN1, CUTC,
Protein Size: 706

Molecular Weight: 78 kDa

Gene ID: 55191

NCBI Accession: NM_018161, NP_060631

UniProt: Q6IA69