P4HA3 antibody (N-Term)
Quick Overview for P4HA3 antibody (N-Term) (ABIN2790667)
Target
See all P4HA3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- EDSTTPVANP LLAFTLIKRL QSDWRNVVHS LEASENIRAL KDGYEKVEQD
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Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against P4HA3. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human P4HA3
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 544 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- P4HA3 (Prolyl 4-Hydroxylase, alpha Polypeptide III (P4HA3))
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Alternative Name
- P4HA3
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Background
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This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Alias Symbols: -
Protein Interaction Partner: WDR62, MAGEA2B, NUTM1, DTNBP1, ZC3H12A, MAGEC2, SERTAD1, HGS, MEOX2, NDN, P4HB, PDIA2,
Protein Size: 544 -
Molecular Weight
- 60 kDa
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Gene ID
- 283208
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NCBI Accession
- NM_182904, NP_878907
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UniProt
- Q7Z4N8
Target
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