CRNKL1 antibody (C-Term)

Catalog No. ABIN2790747

This Rabbit Polyclonal antibody specifically detects CRNKL1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse and Rabbit.

Quick Overview for CRNKL1 antibody (C-Term) (ABIN2790747)

Target: CRNKL1 (Crooked Neck Pre-mRNA Splicing Factor-Like 1 (CRNKL1))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRNKL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CRNKL1 Antibody

Binding Specificity: C-Term

Sequence: SFEEEFGTAS DKERVDKLMP EKVKKRRKVQ TDDGSDAGWE EYFDYIFPED

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CRNKL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CRNKL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 848 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRNKL1

Target: CRNKL1 (Crooked Neck Pre-mRNA Splicing Factor-Like 1 (CRNKL1))

Alternative Name: CRNKL1

Background: The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. This gene is similar in sequence to crn and encodes a protein which can localize to pre-mRNA splicing complexes in the nucleus. The encoded protein, which contains many tetratricopeptide repeats, is required for pre-mRNA splicing.
Alias Symbols: CLF, CRN, Clf1, HCRN, MSTP021, SYF3
Protein Interaction Partner: SUMO2, UBC, RNF2, BMI1, SUZ12, EED, CCDC12, EIF4A3, MAGOH, SNRNP200, PRPF8, SMARCD3, DHX8, SIRT7, SLC2A4, BID, Cdc5l, Snw1, PPIL2, HSP90AA1,
Protein Size: 848

Molecular Weight: 93 kDa

Gene ID: 51340

NCBI Accession: NM_016652, NP_057736

UniProt: Q9BZJ0

Pathways: Ribonucleoprotein Complex Subunit Organization