CRNKL1 antibody (C-Term)

Catalog No. ABIN2790747

Product Details anti-CRNKL1 Antibody

Target: CRNKL1 (Crooked Neck Pre-mRNA Splicing Factor-Like 1 (CRNKL1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRNKL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SFEEEFGTAS DKERVDKLMP EKVKKRRKVQ TDDGSDAGWE EYFDYIFPED

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CRNKL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CRNKL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 848 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CRNKL1

Target: CRNKL1 (Crooked Neck Pre-mRNA Splicing Factor-Like 1 (CRNKL1))

Alternative Name: CRNKL1 (CRNKL1 Products)

Background: The crooked neck (crn) gene of Drosophila is essential for embryogenesis and is thought to be involved in cell cycle progression and pre-mRNA splicing. This gene is similar in sequence to crn and encodes a protein which can localize to pre-mRNA splicing complexes in the nucleus. The encoded protein, which contains many tetratricopeptide repeats, is required for pre-mRNA splicing.
Alias Symbols: CLF, CRN, Clf1, HCRN, MSTP021, SYF3
Protein Interaction Partner: SUMO2, UBC, RNF2, BMI1, SUZ12, EED, CCDC12, EIF4A3, MAGOH, SNRNP200, PRPF8, SMARCD3, DHX8, SIRT7, SLC2A4, BID, Cdc5l, Snw1, PPIL2, HSP90AA1,
Protein Size: 848

Molecular Weight: 93 kDa

Gene ID: 51340

NCBI Accession: NM_016652, NP_057736

UniProt: Q9BZJ0

Pathways: Ribonucleoprotein Complex Subunit Organization