RAB3GAP2
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
Biotin
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
RAB3GAP2
(RAB3 GTPase Activating Protein Subunit 2 (Non-Catalytic) (RAB3GAP2))
Alternative Name
RAB3GAP2
Background
The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome. Protein Interaction Partner: UBC, RAB3GAP1, VAPA, VAPB, GABPA, TSEN34, SMARCAD1, NUDCD3, RBM12, GNE, EXOSC6, VCP, PAXIP1, NUP43, RBM26, UTP20, SHC1, LMAN1, MAP1LC3A, FEZ1, PTP4A3, Protein Size: 206