DENND4C antibody (C-Term)

Catalog No. ABIN2790996

The Rabbit Polyclonal anti-DENND4C antibody has been validated for WB. It is suitable to detect DENND4C in samples from Human, Cow, Dog, Horse, Guinea Pig and Rabbit.

Quick Overview for DENND4C antibody (C-Term) (ABIN2790996)

Target: DENND4C (DENN/MADD Domain Containing 4C (DENND4C))

Reactivity: Human, Cow, Dog, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DENND4C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DENND4C Antibody

Binding Specificity: C-Term

Sequence: KHNQIITEET GSAVEPSDEI KRASGDVQTM KISSVPNSLS KRNVSLTRSH

Predicted Reactivity: Cow: 85%, Dog: 86%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Rabbit: 83%

Characteristics: This is a rabbit polyclonal antibody against DENND4C. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND4C

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DENND4C

Target: DENND4C (DENN/MADD Domain Containing 4C (DENND4C))

Alternative Name: DENND4C

Background: DENND4C is guanine nucleotide exchange factor (GEF) activating RAB10. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.
Protein Interaction Partner: FBXW11, YWHAB, UBC,
Protein Size: 791

Molecular Weight: 87 kDa

Gene ID: 55667