NDUFA12 antibody (N-Term)

Catalog No. ABIN2791134

The Rabbit Polyclonal anti-NDUFA12 antibody has been validated for WB. It is suitable to detect NDUFA12 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae, Sheep and Zebrafish (Danio rerio).

Quick Overview for NDUFA12 antibody (N-Term) (ABIN2791134)

Target: NDUFA12 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 12 (NDUFA12))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NDUFA12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NDUFA12 Antibody

Binding Specificity: N-Term

Sequence: VLKRGLQQIT GHGGLRGYLR VFFRTNDAKV GTLVGEDKYG NKYYEDNKQF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 100%, Yeast: 91%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against NDUFA12. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NDUFA12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 145 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NDUFA12

Target: NDUFA12 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, 12 (NDUFA12))

Alternative Name: NDUFA12

Background: This gene encodes a protein which is part of mitochondrial complex 1, part of the oxidative phosphorylation system in mitochondria. Complex 1 transfers electrons to ubiquinone from NADH which establishes a proton gradient for the generation of ATP. Mutations in this gene are associated with Leigh syndrome due to mitochondrial complex 1 deficiency. Pseudogenes of this gene are located on chromosomes 5 and 13. Alternative splicing results in multiple transcript variants.
Alias Symbols: B17.2, DAP13
Protein Interaction Partner: UBC, MMGT1, TOMM22, MRPL15, ERLIN1, ATP5H, SURF1, NDUFS4, NDUFS1, NDUFB9, NDUFA9, NDUFA2, MPV17, CYC1, COX15, ATP5C1, ATP5B, ABCD1, ZNF768,
Protein Size: 145

Molecular Weight: 15 kDa

Gene ID: 55967

NCBI Accession: NM_018838, NP_061326

UniProt: Q9UI09