CDC34 antibody (Middle Region)

Catalog No. ABIN2792175

This Rabbit Polyclonal antibody specifically detects CDC34 in WB and IHC. It exhibits reactivity toward Rat, Cow and Dog.

Quick Overview for CDC34 antibody (Middle Region) (ABIN2792175)

Target: CDC34 (Cell Division Cycle 34 (CDC34))

Reactivity: Rat, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC34 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CDC34 Antibody

Binding Specificity: Middle Region

Sequence: TLAEYCVKTK APAPDEGSDL FYDDYYEDGE VEEEADSCFG DDEDDSGTEE

Predicted Reactivity: Cow: 100%, Dog: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CDC34. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC34

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 236 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDC34

Target: CDC34 (Cell Division Cycle 34 (CDC34))

Alternative Name: CDC34

Background: CDC34 catalyzes the covalent attachment of ubiquitin to other proteins. CDC34 may be involved in degradation of katenin.The protein encoded by this gene is a member of the ubiquitin-conjugating enzyme family. Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins. This protein is a part of the large multiprotein complex, which is required for ubiquitin-mediated degradation of cell cycle G1 regulators, and for the initiation of DNA replication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: E2-CDC34, UBC3, UBE2R1, UBCH3
Protein Interaction Partner: FBXW11, UBC, RBX1, SIAH1, SDCBP, PPARG, ZNRF1, FBXW7, BTRC, UBA1, CDC34, HIST1H2BA, UBI4, MARCH1, MARCH2, GNPDA1, USP5, WARS, RAD23A, ANAPC11, ING4, FBXL2, Rag1, FBXO32, ITCH, NEDD4L, WWP2, TRIM28, RNF7, CUL1, CUL3, VHL, TRIM21, SKP2, CDKN1B, CCNE1, ZFAND
Protein Size: 236

Molecular Weight: 27 kDa

Gene ID: 997

NCBI Accession: NM_004359, NP_004350

UniProt: P49427