RGS5 antibody (Middle Region)

Catalog No. ABIN2792216

This Rabbit Polyclonal antibody specifically detects RGS5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig and Pig.

Quick Overview for RGS5 antibody (Middle Region) (ABIN2792216)

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS5 Antibody

Binding Specificity: Middle Region

Sequence: PDSVGDLVIP YNEKPEKPAK TQKTSLDEAL QWRDSLDKLL QNNYGLASFK S

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 84%, Pig: 76%, Rat: 84%

Characteristics: This is a rabbit polyclonal antibody against RGS5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RGS5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 181 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS5

Target: RGS5 (Regulator of G-Protein Signaling 5 (RGS5))

Alternative Name: RGS5

Background: The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators.The regulator of G protein signaling (RGS) proteins are signal transduction molecules that have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. Multiple genes homologous to SST2 are present in higher eukaryotes. RGS proteins are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-663 AU130764.1 1-663 664-2587 BX537427.1 499-2422 2588-3235 BU187973.1 34-681 3236-3746 AL600981.1 90-600 3747-4143 AA486366.1 76-472 4144-4358 AA974387.1 113-327 c 4359-4664 BX537427.1 4194-4499 4665-5573 AF176919.1 724-1632 5574-5848 BX537427.1 5409-5683
Alias Symbols: MST092, MST106, MST129, MSTP032, MSTP092, MSTP106, MSTP129
Protein Interaction Partner: ADRB2, APP, GNAQ, GNAI3, GNAI2, GNAO1, GNAI1,
Protein Size: 181

Molecular Weight: 21 kDa

Gene ID: 8490

NCBI Accession: NM_003617, NP_003608

UniProt: O15539

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling