TRH antibody (C-Term)

Catalog No. ABIN2792302

This Rabbit Polyclonal antibody specifically detects TRH in WB. It exhibits reactivity toward Human, Cow, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for TRH antibody (C-Term) (ABIN2792302)

Target: TRH (Thyrotropin-Releasing Hormone (TRH))

Reactivity: Human, Cow, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRH Antibody

Binding Specificity: C-Term

Sequence: RALGGPCGPQ GAYGQAGLLL GLLDDLSRSQ GAEEKRQHPG RRAAWVREPL

Specificity: This antibody is directed towards the pro-hormone form of TRH, not the processed tripeptide.

Predicted Reactivity: Cow: 100%, Guinea Pig: 84%, Human: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against TRH. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TRH

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 242 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRH

Target: TRH (Thyrotropin-Releasing Hormone (TRH))

Alternative Name: TRH

Background: TRH functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
Alias Symbols: MGC125964, MGC125965
Protein Interaction Partner: TRHR, CPE, ARRB2,
Protein Size: 242

Molecular Weight: 26 kDa

Gene ID: 7200

NCBI Accession: NM_007117, NP_009048

UniProt: P20396

Pathways: Positive Regulation of Peptide Hormone Secretion, Feeding Behaviour