GIP antibody (N-Term)

Catalog No. ABIN2793043

This Rabbit Polyclonal antibody specifically detects GIP in WB, IHC and FACS. It exhibits reactivity toward Human.

Quick Overview for GIP antibody (N-Term) (ABIN2793043)

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-GIP Antibody

Binding Specificity: AA 7-38, N-Term

Purpose: Rabbit Anti-Human GIPR (N-term) Antibody

Immunogen: This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-38 amino acids from the N-terminal region of human GIPR.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry, Flow Cytometry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50, FC: 1:10-50Western blot analysis of GIPR antibody (N-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.000 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for GIP

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Alternative Name: GIP

Background:

Target Description: GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.

Gene Symbol: GIPR

Molecular Weight: 53157 Da

Gene ID: 2696

UniProt: P48546

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism