Transglutaminase antibody (AA 413-442)

Catalog No. ABIN2793239

The Rabbit Polyclonal anti-Transglutaminase antibody has been validated for WB. It is suitable to detect Transglutaminase in samples from Human.

Quick Overview for Transglutaminase antibody (AA 413-442) (ABIN2793239)

Target: Transglutaminase

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Transglutaminase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Transglutaminase Antibody

Binding Specificity: AA 413-442

Purpose: Rabbit Anti-Human Transglutaminase (TGM2) (Center T428) Antibody

Immunogen: This Transglutaminase (TGM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-442 amino acids from the Central region of human Transglutaminase (TGM2).

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of TGM2 (arrow) using rabbit polyclonal TGM2 Antibody (Center T428) .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Transglutaminase

Target: Transglutaminase

Background:

Target Description: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.

Gene Symbol: TGM2

Molecular Weight: 77329 Da

Gene ID: 7052

UniProt: P21980