Transglutaminase antibody (AA 429-458)
Quick Overview for Transglutaminase antibody (AA 429-458) (ABIN2793240)
Target
See all Transglutaminase AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- AA 429-458
-
Purpose
- Rabbit Anti-Human Transglutaminase (TGM2) (Center K444) Antibody
-
Immunogen
- This Transglutaminase (TGM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 429-458 amino acids from the Central region of human Transglutaminase (TGM2).
-
Isotype
- Ig Fraction
-
-
anti-Transglutaminase (AA 461-560) antibody
Reactivity: Human, Rat ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Transglutaminase (AA 429-458) antibodyReactivity: Human WB, IHC (p), IF Host: Rabbit Polyclonal unconjugated
-
-
Application Notes
-
Western Blot, Immunofluorescence, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IF: 1:10-50, IHC: 1:10-50TGM2 Antibody (Center K444) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 2.0 mg/mL
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- 2-8°C (short-term), -20°C (long-term)
-
-
- Transglutaminase
-
Background
-
Target Description: Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.
Gene Symbol: TGM2
-
Molecular Weight
- 77329 Da
-
Gene ID
- 7052
-
UniProt
- P21980
Target
-
