USP39 antibody (N-Term)

Catalog No. ABIN2793377

The Rabbit Polyclonal anti-USP39 antibody has been validated for WB. It is suitable to detect USP39 in samples from Human.

Quick Overview for USP39 antibody (N-Term) (ABIN2793377)

Target: USP39 (Ubiquitin Specific Peptidase 39 (USP39))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP39 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-USP39 Antibody

Binding Specificity: AA 108-139, N-Term

Purpose: Rabbit Anti-Human SAD1 (BRSK1) (N-term) Antibody

Immunogen: This SAD1 (BRSK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-139 amino acids from the N-terminal region of human SAD1 (BRSK1).

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of anti-KIAA181 Pab was detected using the purified Pab.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2.0 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for USP39

Target: USP39 (Ubiquitin Specific Peptidase 39 (USP39))

Alternative Name: SAD1

Background:

Target Description: BRSK1 may be involved as a checkpoint kinase in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. This protein phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. BRSK1 is partitioned between cytoplasmic and nuclear locations in the absence of DNA damage, but translocates to the nucleus in response to Uv- or MMS-induced DNA damage. BRSK1 shares significant homology with the fission yeast Cdr2, a mitosis-regulatory kinase, and Caenorhabditis elegans SAD1, a neuronal cell polarity regulator. The BRSK1 transcript is expressed ubiquitously with the highest levels of expression in brain and testis.

Gene Symbol: BRSK1

Molecular Weight: 85087 Da

Gene ID: 84446

UniProt: Q8TDC3

Pathways: Ribonucleoprotein Complex Subunit Organization