VEGF1 antibody (N-Term)
Quick Overview for VEGF1 antibody (N-Term) (ABIN2794871)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 66-95, N-Term
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Purpose
- Rabbit Anti-Human VEGF1 (N-term) Antibody
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Immunogen
- This VEGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human VEGF1.
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Isotype
- Ig Fraction
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anti-PDGF and VEGF-Related Factor 1 (PVF1) (AA 66-95), (N-Term) antibody
PVF1 Reactivity: Human WB Host: Rabbit Polyclonal RB11708 unconjugated
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Application Notes
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Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of VEGF1 Antibody (N-term) polyclonal antibody. Molecular weight of monomeric VEGF1 is 27042 Da, higher observed molecular weight band is consistent with common form of disulfide linked homodimer. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 2.0 mg/mL
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Storage
- 4 °C,-20 °C
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Storage Comment
- 2-8°C (short-term), -20°C (long-term)
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- VEGF1 (PVF1) (PDGF and VEGF-Related Factor 1 (PVF1))
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Alternative Name
- VEGF1
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Background
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Target Description: VEGF1 is a member of the PDGF/VEGF growth factor family and and is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF1 have been associated with proliferative and nonproliferative diabetic retinopathy.
Gene Symbol: VEGFA
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Molecular Weight
- 27042 Da
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Gene ID
- 7422
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UniProt
- P15692
Target
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