HERV antibody (Center)

Catalog No. ABIN2796407

The Rabbit Polyclonal anti-HERV antibody has been validated for WB. It is suitable to detect HERV in samples from Human.

Quick Overview for HERV antibody (Center) (ABIN2796407)

Target: HERV (Human Endogenous Retrovirus (HERV))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HERV antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HERV Antibody

Binding Specificity: AA 400-429, Center

Purpose: Rabbit Anti-Human HERV (ERVWE1) (Center) Antibody

Immunogen: This HERV (ERVWE1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-429 amino acids from the Central region of human HERV (ERVWE1).

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of lysate from human brain tissue lysate, using Syncytin(ERVWE1) Antibody at 1:5000 dilution was used as the secondary antibody. Lysate at 35 μg per lane.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.900 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for HERV

Target: HERV (Human Endogenous Retrovirus (HERV))

Alternative Name: HERV

Target Type: Virus

Background:

Target Description: Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. The protein, also known as syncytin, is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. This protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.

Gene Symbol: ERVW-1

Molecular Weight: 59866 Da

Gene ID: 30816

UniProt: Q9UQF0