Glucagon antibody (AA 119-148)

Catalog No. ABIN2796649

This Mouse Monoclonal antibody specifically detects Glucagon in WB and Agon. It exhibits reactivity toward Human.

Quick Overview for Glucagon antibody (AA 119-148) (ABIN2796649)

Target: Glucagon (GCG)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glucagon antibody is un-conjugated

Application: Western Blotting (WB), Agonist (Agon)

Product Details anti-Glucagon Antibody

Binding Specificity: AA 119-148

Purpose: Mouse Anti-Human Glucagon Antibody

Immunogen: This Glucagon antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 119-148 amino acids from human Glucagon.

Isotype: IgG1 kappa

Application Details

Application Notes: Western Blot
Recommended Dilutions
WB: 1:100-500Glucagon Antibody .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Glucagon

Target: Glucagon (GCG)

Alternative Name: Glucagon

Background:

Target Description: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Gene Symbol: GCG

Molecular Weight: 20909 Da

Gene ID: 2641

UniProt: P01275

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling