CCR8 antibody (C-Term)

Catalog No. ABIN2797017

This anti-CCR8 antibody is a Rabbit Polyclonal antibody detecting CCR8 in WB and FACS. Suitable for Human.

Quick Overview for CCR8 antibody (C-Term) (ABIN2797017)

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR8 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-CCR8 Antibody

Binding Specificity: AA 290-317, C-Term

Purpose: Rabbit Anti-Human CCR8 (C-term) Antibody

Immunogen: This CCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-317 amino acids from the C-terminal region of human CCR8.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Flow Cytometry
Recommended Dilutions
WB: 1:1000, FC: 1:10-50CCR8 Antibody (C-term) .FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Alternative Name: CCR8

Background:

Target Description: CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.

Gene Symbol: CCR8

Molecular Weight: 40844 Da

Gene ID: 1237

UniProt: P51685