Cofilin 2 antibody (N-Term)

Catalog No. ABIN2798438

The Rabbit Polyclonal anti-Cofilin 2 antibody has been validated for WB and IHC. It is suitable to detect Cofilin 2 in samples from Human.

Quick Overview for Cofilin 2 antibody (N-Term) (ABIN2798438)

Target: Cofilin 2 (CFL2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cofilin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Cofilin 2 Antibody

Binding Specificity: AA 25-54, N-Term

Purpose: Rabbit Anti-Human CFL2 (N-term) Antibody

Immunogen: This CFL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human CFL2.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of lysate from NCI-H1299 cell line, using CFL2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.480 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Cofilin 2

Target: Cofilin 2 (CFL2)

Alternative Name: CFL2

Background:

Target Description: This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

Gene Symbol: CFL2

Molecular Weight: 18737 Da

Gene ID: 1073

UniProt: Q9Y281

Pathways: Caspase Cascade in Apoptosis