Desmoglein 1 antibody (Center)

Catalog No. ABIN2798593

This Rabbit Polyclonal antibody specifically detects Desmoglein 1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Desmoglein 1 antibody (Center) (ABIN2798593)

Target: Desmoglein 1 (DSG1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmoglein 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Desmoglein 1 Antibody

Binding Specificity: AA 471-499, Center

Purpose: Rabbit Anti-Human DSG1 (Center) Antibody

Immunogen: This DSG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-499 amino acids from the Central region of human DSG1.

Isotype: Ig Fraction

Application Details

Application Notes: Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50DSG1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Storage: 4 °C,-20 °C

Storage Comment: 2-8°C (short-term), -20°C (long-term)

Target Details for Desmoglein 1

Target: Desmoglein 1 (DSG1)

Alternative Name: DSG1

Background:

Target Description: Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. The protein encoded by this gene has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.

Gene Symbol: DSG1

Molecular Weight: 113748 Da

Gene ID: 1828

UniProt: Q02413

Pathways: Cell-Cell Junction Organization